Endocrine Abstracts

Introduction: Weakness is one of the most common complaints among the patients. Clinical manifestations of a hypopituitarism depend on the extent of hormone deficiency and may be non-specific and thus the diagnosis is often missed. The progressive loss of pituitary hormone secretion is usually a slow process, which can occur over a period of months or years.Clinical case: A 62 years old women who complained of mild weakness mostly in the evenings in the ...

Oral glucose tolerance test (OGTT) is the main tool in population based screening for type 2 diabetes mellitus. Sometimes OGTT results are showing asymptomatic lowering of post-load blood glucose. Post-load plasma glucose (2hPG) level 3.9 mmol/l (70 mg/dl) and lower shows biochemical hypoglycaemia. Biochemical hypoglycaemia might be observed among individuals with abnormal glucose tolerance and in healthy population. The objective of the investigation was to assess a prevalenc...

Hyperprolactinaemia is a common endocrine disorder. Causes are related to physiological factors, pharmacological intervention and pathological conditions. There are a wide variety of drugs that can induce a significant hyperprolactinaemia frequently associated with clinical symptoms. The aim was to analyse clinical manifestation of hyperprolactinaemia in routine clinical practice.Material and methods: We conducted retrospective review of medical records ...

Introduction: The Ehlers-Danlos syndrome, classic type is a connective tissue disorder, characterized by skin hyperextensibility, abnormal wound healing, and joint hypermobility, due to COL5A1 or COL5A2 genes mutations. Multiple endocrine neoplasia, type 2A (MEN2A) is a syndrome defined by medullary carcinoma, phaeochromocytoma, hyperparathyroidism, and occasionally cutaneous lichen amyloidosis, because of mutations in RET proto-oncogene. COL5A</...